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Clostridium difficile
Clostridium difficile
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Clostridium difficile
strains...
Clostridium difficile
Clostridium difficile
(1982 + USA)
Clostridium difficile
(1982–2004)
Clostridium difficile
(1983–2004 + USA)
Clostridium difficile
(1987 + Italy)
Clostridium difficile
(1991 + France)
Clostridium difficile
(1991 + USA)
Clostridium difficile
(1997 + Belgium)
Clostridium difficile
(2000 + Italy)
Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Antimicrobial
Reference
Clostridium difficile
0.0015
-
? - ?
Rifampicin (Rifampin)
1082
Clostridium difficile
0.004
-
? - ?
Rifalazil (ABI-1648, KRM-1648)
1081
Clostridium difficile
0.006
-
? - ?
Rifalazil (ABI-1648, KRM-1648)
1082
Clostridium difficile
0.0075
0.015
0.0038 - >16
Rifaximin (Xifaxan)
480
Clostridium difficile
0.0075
0.03
0.0019 - >16
Rifalazil (ABI-1648, KRM-1648)
480
Clostridium difficile
<0.015
<0.015
<0.015 - ?
ABT-492
3
Clostridium difficile
0.016
0.125
≤0.016 - 0.25
OPT-80
241
Clostridium difficile
0.03
0.03
0.03 - ?
Ranbezolid (RBX 7644)
1466
Clostridium difficile
0.06
0.125
0.03 - 0.5
Nitazoxanide
480
Clostridium difficile
0.06
0.125
≤0.06 - 2
Tigecycline (GAR-936, Tigacyl)
497
Clostridium difficile
0.06
0.1285
0.015 - 0.5
Tizoxanide (TZO)
480
Clostridium difficile
0.06
0.25
? - ?
Clinafloxacin (PD 127391)
307
Clostridium difficile
0.06
1
0.03 - 256
Telithromycin (HMR 3647, RU-66647, Ketek)
948
Clostridium difficile
0.12
0.12
0.03 - 1
Sitafloxacin
12
Clostridium difficile
0.125
0.125
0.015 - 0.25
OPT-80
480
Clostridium difficile
0.125
0.125
? - ?
Metronidazole (Flagyl)
381
Clostridium difficile
0.125
0.25
0.025 - 0.5
Metronidazole (Flagyl)
480
Clostridium difficile
0.125
0.25
0.03 - 1
Tinidazole (Tindamax Fasigyn)
480
Clostridium difficile
0.125
0.25
0.06 - 1
Tigecycline (GAR-936, Tigacyl)
480
Clostridium difficile
0.125
0.25
0.125 - 0.25
Metronidazole (Flagyl)
948
Clostridium difficile
0.125
1
0.125 - 2
DX-619
1477
Clostridium difficile
0.125
4
? - ?
SCH29482
1385
Clostridium difficile
0.125
4
? - ?
SCH34343
1385
Clostridium difficile
0.25
0.25
0.12 - 8
Clinafloxacin (PD 127391)
12
Clostridium difficile
0.25
0.25
0.125 - 0.25
Teicoplanin (Targocid)
1466
Clostridium difficile
0.25
0.25
0.125 - 0.5
Dalbavancin
29
Clostridium difficile
0.25
0.25
0.125 - 0.5
Telavancin (TD-6424, Vibativ)
1457
Clostridium difficile
0.25
0.25
0.25 - 0.5
Metronidazole (Flagyl)
1469
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