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Clostridium difficile
Clostridium difficile
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Clostridium difficile
strains...
Clostridium difficile
Clostridium difficile
(1982 + USA)
Clostridium difficile
(1982–2004)
Clostridium difficile
(1983–2004 + USA)
Clostridium difficile
(1987 + Italy)
Clostridium difficile
(1991 + France)
Clostridium difficile
(1991 + USA)
Clostridium difficile
(1997 + Belgium)
Clostridium difficile
(2000 + Italy)
Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Antimicrobial
Reference
Clostridium difficile
≤0.25
≤0.25
≤0.25 - ?
Minocycline (Minocycline hydrochloride, Minocin)
462
Clostridium difficile
≤0.25
≤0.25
≤0.25 - ?
Tigecycline (GAR-936, Tigacyl)
462
Clostridium difficile
0.25
0.5
0.06 - 0.5
Ramoplanin
480
Clostridium difficile
0.25
0.5
≤0.125 - 0.5
Metronidazole (Flagyl)
241
Clostridium difficile
0.25
0.5
0.125 - 1
Metronidazole (Flagyl)
29
Clostridium difficile
0.25
0.5
0.25 - 0.5
Metronidazole (Flagyl)
268
Clostridium difficile
0.25
0.5
0.25 - 0.5
Metronidazole (Flagyl)
1473
Clostridium difficile
0.25
0.5
0.25 - 0.5
Metronidazole (Flagyl)
1466
Clostridium difficile
0.25
1
0.25 - 2
Quinupristin/Dalfopristin (Synercid)
1457
Clostridium difficile
0.25
2
0.125 - 16
Virginiamycin
764
Clostridium difficile
0.25
4
0.25 - 4
ACH-702
1279
Clostridium difficile
0.25
16
0.25 - 256
Erythromycin (E-mycin, Ery-tab, Benzamycin)
948
Clostridium difficile
0.25
>32
0.06 - >32
Telithromycin (HMR 3647, RU-66647, Ketek)
1460
Clostridium difficile
0.25
64
0.125 - 128
Tylosin
764
Clostridium difficile
0.5
0.5
0.06 - 0.5
Teicoplanin (Targocid)
241
Clostridium difficile
0.5
0.5
0.25 - 1
Metronidazole (Flagyl)
1460
Clostridium difficile
0.5
0.5
0.25 - 1
Metronidazole (Flagyl)
1474
Clostridium difficile
≤0.5
≤0.5
≤0.5 - ?
Metronidazole (Flagyl)
462
Clostridium difficile
0.5
1
≤0.06 - 1
Metronidazole (Flagyl)
497
Clostridium difficile
0.5
1
0.125 - 1
Daptomycin + 50 μg/ml Ca++
490
Clostridium difficile
0.5
1
0.25 - 2
Vancomycin (Vancocyn, Lyphocin)
1457
Clostridium difficile
0.5
1
0.25 - 4
Metronidazole (Flagyl)
1470
Clostridium difficile
0.5
2
0.5 - 2
Amoxicillin-clavulanate
1469
Clostridium difficile
0.5
2
0.5 - 2
Daptomycin (Cubicin)
1457
Clostridium difficile
0.5
4
0.25 - 8
Quinupristin/Dalfopristin (Synercid)
29
Clostridium difficile
0.5
4
? - ?
Piperacillin (Pipracil)
381
Clostridium difficile
0.5
16
? - ?
Cefamandole (Mandol)
1389
Clostridium difficile
0.5
>32
0.125 - >32
Clarithromycin (Biaxin)
1460
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