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Tigecycline (GAR-936, Tigacyl)
Tigecycline (GAR-936, Tigacyl)
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Streptococcus agalactiae
≤0.12
≤0.12
≤0.12 - ?
89
Streptococcus agalactiae
0.12
0.12
0.12 - ?
175
Streptococcus agalactiae
-
-
0.06 - 0.25
311
Streptococcus anginosus
0.015
0.12
<0.015 - 0.5
6
Streptococcus bovis
0.06
0.06
0.03 - 0.12
462
Streptococcus constellatus
0.015
0.12
<0.015 - 0.5
6
Streptococcus intermedius
0.015
0.12
<0.015 - 0.5
6
Streptococcus intermedius
0.25
0.5
0.03 - 1
472
Streptococcus mutans
0.015
0.12
<0.015 - 0.5
6
Streptococcus oralis
0.015
0.12
<0.015 - 0.5
6
Streptococcus parasanguis
0.015
0.12
<0.015 - 0.5
6
Streptococcus pneumonia
<0.015
<0.015
<0.015 - 0.03
6
Streptococcus pneumonia
0.06
0.5
≤0.008 - 1
42
Streptococcus pneumonia
0.075
0.28
<0.015 - 1
162
Streptococcus pneumonia
≤0.12
≤0.12
≤0.12 - 0.25
472
Streptococcus pneumonia
(1020)
-
-
0.06 - ?
34
Streptococcus pneumonia
(1199)
-
-
0.06 - ?
34
Streptococcus pneumonia
(1293)
-
-
0.06 - ?
34
Streptococcus pneumonia
(1396)
-
-
0.12 - ?
34
Streptococcus pneumonia
(ATCC 10813)
-
-
0.12 - ?
34
Streptococcus pneumonia
(ATCC 49619)
-
-
0.03 - ?
34
Streptococcus pneumonia
(high-level penicillin-resistant)
-
-
0.06 - 0.25
24
Streptococcus pneumonia
(penicillin-intermediate)
0.03
0.03
0.015 - 0.12
462
Streptococcus pneumonia
(penicillin-intermediate)
0.06
0.25
? - ?
36
Streptococcus pneumonia
(penicillin-intermediate)
≤0.12
≤0.12
? - ?
39
Streptococcus pneumonia
(penicillin-intermediate)
0.25
0.25
0.12 - 0.25
16
Streptococcus pneumonia
(penicillin-intermediate)
0.5
0.5
0.25 - 0.5
175
Streptococcus pneumonia
(penicillin-intermediate)
0.5
1
≤0.12 - 2
89
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