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Tigecycline (GAR-936, Tigacyl)
Tigecycline (GAR-936, Tigacyl)
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Streptococcus pneumonia
(penicillin-intermediate-resistant)
0.06
0.125
≤0.06 - 0.125
497
Streptococcus pneumonia
(penicillin-resistant)
0.03
0.03
0.015 - 0.12
462
Streptococcus pneumonia
(penicillin-resistant)
0.06
0.12
0.03 - 0.25
476
Streptococcus pneumonia
(penicillin-resistant)
0.06
0.25
0.015 - 0.5
42
Streptococcus pneumonia
(penicillin-resistant)
0.06
0.25
? - ?
36
Streptococcus pneumonia
(penicillin-resistant)
≤0.12
≤0.12
? - ?
39
Streptococcus pneumonia
(penicillin-resistant)
0.25
0.25
0.25 - ?
16
Streptococcus pneumonia
(penicillin-resistant)
0.25
0.5
0.25 - 0.5
175
Streptococcus pneumonia
(penicillin-resistant)
0.25
1
≤0.12 - 2
89
Streptococcus pneumonia
(penicillin-susceptible)
0.03
0.03
0.008 - 0.06
462
Streptococcus pneumonia
(penicillin-susceptible)
0.06
0.12
0.03 - 0.25
476
Streptococcus pneumonia
(penicillin-susceptible)
≤0.12
≤0.12
? - ?
39
Streptococcus pneumonia
(penicillin-susceptible)
0.12
0.5
? - ?
36
Streptococcus pneumonia
(penicillin-susceptible)
0.25
0.25
0.25 - 0.5
16
Streptococcus pneumonia
(penicillin-susceptible)
0.5
0.5
0.25 - 1
175
Streptococcus pneumonia
(penicillin-susceptible)
0.5
1
≤0.12 - 1
89
Streptococcus pyogenes
0.03
0.06
0.016 - 0.06
98
Streptococcus pyogenes
0.06
0.06
0.06 - 0.12
214
Streptococcus pyogenes
0.06
0.12
0.03 - 0.25
311
Streptococcus pyogenes
0.12
0.12
0.03 - 0.12
175
Streptococcus pyogenes
0.12
0.12
0.06 - 0.25
476
Streptococcus pyogenes
0.25
0.25
≤0.12 - 0.25
89
Streptococcus
spp. (Viridans group)
0.03
0.12
0.008 - 0.5
462
Streptococcus uberis
0.015
0.12
<0.015 - 0.5
6
Yersinia enterocolitica
0.25
0.5
0.12 - 0.5
462
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