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Tigecycline (GAR-936, Tigacyl)
Tigecycline (GAR-936, Tigacyl)
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Pneumococci (penicillin-intermediate)
0.03
0.06
<0.016 - 0.125
46
Pneumococci (penicillin-intermediate)
0.06
0.125
<0.016 - 0.125
46
Pneumococci (penicillin-susceptible)
0.03
0.125
<0.016 - 0.125
46
Propionibacterium acnes
0.25
0.5
0.06 - 0.5
1476
Propionibacterium
spp.
0.25
0.5
0.125 - 0.5
1476
Proteae (indole-positive + tetracycline-resistant)
2
4
0.06 - 16
158
Proteae (indole-positive + tetracycline-susceptible)
1
2
0.06 - 8
158
Proteus mirabilis
4
8
2 - >8
462
Proteus mirabilis
(tetracycline-resistant)
4
4
0.25 - 16
158
Proteus mirabilis
(tetracycline-susceptible)
2
-
1 - 8
158
Proteus vulgaris
4
8
2 - 8
462
Providencia rettgeri
4
8
2 - 8
462
Providencia stuartii
4
8
1 - 8
462
Pseudomonas aeruginosa
>8
>8
4 - >8
462
Pseudomonas aeruginosa
8
16
0.25 - >32
472
Pseudomonas aeruginosa
8
16
4 - 32
497
Pseudomonas aeruginosa
>8
>16
? - ?
36
Pseudomonas aeruginosa
>=8
≥32
≤0.008 - >=32
475
Pseudomonas aeruginosa
>16
>16
0.25 - >16
42
Pseudomonas aeruginosa
>16
>16
1 - >16
55
Pseudomonas aeruginosa
-
-
2 - 32
656
Pseudomonas aeruginosa
(1019)
-
-
2 - ?
656
Pseudomonas aeruginosa
(1037)
-
-
8 - ?
656
Pseudomonas aeruginosa
(956)
-
-
32 - ?
656
Pseudomonas
spp.
>1
>8
0.5 - >8
462
Ruminococcus gnavus
-
-
0.094 - ?
1452
Salmonella
spp.
0.5
0.5
0.25 - 2
462
Salmonella
spp. (tetracycline-resistant)
0.5
1
0.12 - 2
158
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