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Co-trimoxazole (Trimethoprim-sulfamethoxazole, TMP-SMX)
Co-trimoxazole (Trimethoprim-sulfamethoxazole, TMP-SMX)
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Enterococcus hirae
>0.5
>2
≤0.5 - >2
462
Enterococcus sp. (Uraguay)
>8
>8
1 - >8
1391
Enterococcus
spp.
>1
>1
≤0.5 - >1
123
Escherichia coli
0.06
2
0.06 - ?
946
Escherichia coli
>0.5
>2
≤0.5 - >2
462
Escherichia coli
-
-
62 - ?
884
Escherichia coli
(ATCC 25922)
-
-
2 - ?
213
Escherichia coli
(enteroaggregative)
-
-
>1024 - ?
478
Escherichia coli
(enterotoxigenic)
-
-
1024 - ?
478
Escherichia coli
(ESBL)
-
-
≤0.06 - >128
447
Haemophilus influenzae
0.12
4
≤0.12 - >16
499
Haemophilus influenzae
0.25
8
<0.25 - >8
85
Haemophilus influenzae
0.25
8
≤0.25 - >8
500
Haemophilus influenzae
>0.5
>4
≤0.5 - >4
412
Haemophilus influenzae
-
-
1 - ?
401
Haemophilus influenzae
(ampicillin-resistant + β-lactamase negative)
>0.25
>2
≤0.25 - >2
462
Haemophilus influenzae
(ESBL)
0.12
8
≤0.12 - 16
499
Haemophilus influenzae
(ESBL)
>0.5
>1
<0.5 - >1
84
Haemophilus influenzae
(non-ESBL)
0.12
4
≤0.12 - >16
499
Haemophilus influenzae
(non-ESBL)
>0.5
>1
≤0.5 - >1
195
Haemophilus influenzae
(non-ESBL)
0.5
1
≤0.5 - >1
114
Haemophilus influenzae
(β-lactamase negative)
>0.25
>2
≤0.25 - >2
462
Haemophilus influenzae
(β-lactamase positive)
>0.25
>2
≤0.25 - >2
462
Haemophilus parasuis
(Spain)
>2
>2
0.5 - 4
768
Hafnia alvei
≤0.5
≤0.5
≤0.5 - >2
462
Klebsiella pneumonia
>0.5
>2
≤0.5 - >2
462
Klebsiella pneumonia
1
-
0.25 - >4
479
Klebsiella pneumonia
-
-
42 - ?
884
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