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Co-trimoxazole (Trimethoprim-sulfamethoxazole, TMP-SMX)
Co-trimoxazole (Trimethoprim-sulfamethoxazole, TMP-SMX)
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Pseudomonas aeruginosa
(ATCC 27853)
-
-
32 - ?
213
Pseudomonas
spp.
>2
>2
>2 - ?
462
Salmonella
sp.
-
-
30 - ?
884
Salmonella
spp.
≤0.5
≤0.5
≤0.5 - >2
462
Salmonella
spp.
-
-
512 - ?
478
Salmonella typhi
-
-
8 - ?
884
Salmonella typhi
-
-
8 - ?
884
Salmonella Weltevreden
-
-
11 - ?
884
Serratia marcescens
0.5
1
≤0.5 - >2
462
Serratia marcescens
>0.5
>4
0.12 - >4
479
Serratia odorifera
>=0.5
≥2
≤0.5 - >2
462
Shigella
10
32
0.02 - 64
1429
Shigella flexneri
-
-
76 - ?
884
Shigella sonnei
>0.5
>2
≤0.5 - >2
462
Shigella
spp.
-
-
>1024 - ?
478
Staphylococci
-
-
10 - 320
1440
Staphylococci (coagulase-negative + methicillin-resistant)
>2
>4
≤0.5 - >4
73
Staphylococci (coagulase-negative + methicillin-susceptible)
>0.5
>4
≤0.5 - >4
73
Staphylococci (coagulase-negative + oxacillin-susceptible)
>0.5
>2
≤0.5 - >2
412
Staphylococci (coagulase-negative)
>0.5
>2
≤0.5 - >2
462
Staphylococci (coagulase-negative)
>1
>1
≤0.5 - >1
123
Staphylococci (coagulase-negative)
>1
>2
≤0.5 - >2
472
Staphylococcus
(coagulase-negative + Uruguay)
0.25
0.5
<0.06 - 8
1391
Staphylococcus
(coagulase-negative)
>0.5
>4
≤0.25 - >4
108
Staphylococcus aureus
≤0.25
≤0.25
≤0.25 - >4
108
Staphylococcus aureus
≤0.5
≤0.5
≤0.5 - >2
472
Staphylococcus aureus
>0.5
>1
≤0.5 - >1
123
Staphylococcus aureus
(ATCC 25923)
-
-
1 - ?
213
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