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Garenoxacin (T-3811, BMS-284756)
Garenoxacin (T-3811, BMS-284756)
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Streptococci (serogroup G)
0.12
0.12
0.06 - 0.12
102
Streptococcus agalactiae
0.1
0.1
0.05 - 0.2
17
Streptococcus agalactiae
0.12
0.25
0.06 - 0.5
102
Streptococcus agalactiae
0.125
0.125
0.03 - 0.125
225
Streptococcus bovis
0.25
0.25
0.125 - 0.5
225
Streptococcus pneumonia
0.03
0.06
≤0.015 - 2
236
Streptococcus pneumonia
-
-
0.007 - 2
956
Streptococcus pneumonia
(ciprofloxacin-resistant)
-
-
0.5 - 2
443
Streptococcus pneumonia
(ciprofloxacin-resistant)
-
-
0.5 - 2
130
Streptococcus pneumonia
(levofloxacin-intermediate-resistant)
0.5
1
0.12 - 2
268
Streptococcus pneumonia
(levofloxacin-resistant)
1
2
0.25 - 2
225
Streptococcus pneumonia
(penicillin-intermediate)
0.06
0.12
0.06 - 0.12
1111
Streptococcus pneumonia
(penicillin-intermediate)
0.12
0.12
0.06 - 0.12
130
Streptococcus pneumonia
(penicillin-intermediate)
0.25
0.25
0.06 - 1
225
Streptococcus pneumonia
(penicillin-intermediate)
-
0.125
? - ?
1044
Streptococcus pneumonia
(penicillin-intermediate-resistant)
0.0025
0.05
0.025 - 0.05
17
Streptococcus pneumonia
(penicillin-intermediate-resistant)
0.06
0.12
0.03 - 2
268
Streptococcus pneumonia
(penicillin-intermediate-resistant)
0.12
0.12
0.06 - 0.12
443
Streptococcus pneumonia
(penicillin-resistant)
0.03
0.125
0.004 - 0.5
225
Streptococcus pneumonia
(penicillin-resistant)
0.06
0.12
0.06 - 0.12
102
Streptococcus pneumonia
(penicillin-resistant)
0.06
0.12
0.06 - 0.12
1111
Streptococcus pneumonia
(penicillin-resistant)
0.12
0.12
0.06 - 0.12
130
Streptococcus pneumonia
(penicillin-resistant)
-
0.063
? - ?
1044
Streptococcus pneumonia
(penicillin-susceptible)
0.05
0.05
0.025 - 0.05
17
Streptococcus pneumonia
(penicillin-susceptible)
0.06
0.12
0.03 - 0.12
268
Streptococcus pneumonia
(penicillin-susceptible)
0.12
0.12
0.03 - 0.12
130
Streptococcus pneumonia
(penicillin-susceptible)
0.12
0.12
0.03 - 0.12
443
Streptococcus pneumonia
(penicillin-susceptible)
0.12
0.12
0.03 - 4
102
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