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Garenoxacin (T-3811, BMS-284756)
Garenoxacin (T-3811, BMS-284756)
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Escherichia coli
0.03
0.12
≤0.03 - >4
1250
Escherichia coli
0.03
8
0.015 - >128
268
Escherichia coli
0.05
0.1
≤0.00625 - 0.2
17
Escherichia coli
0.06
1
≤0.004 - 16
130
Escherichia coli
0.06
1
≤0.004 - 16
443
Escherichia coli
0.06
1
0.015 - >64
225
Escherichia coli
≤-
≤0.06
? - ?
1044
Eubacterium lentum
-
-
0.25 - ?
1476
Eubacterium
spp.
2
2
0.5 - 2
1469
Fusobacteria
0.5
4
0.125 - >32
1469
Fusobacterium mortiferum
0.25
0.25
0.125 - 0.5
1469
Fusobacterium necrophorum
0.25
0.5
0.125 - 0.5
1469
Fusobacterium nucleatum
0.5
0.5
0.25 - 1
1469
Fusobacterium
spp.
-
-
0.125 - 1
225
Fusobacterium varium
4
8
2 - >32
1469
Gardnerella vaginalis
0.5
1
≤0.015 - 8
305
Gardnerella vaginalis
(ATCC 14018)
-
-
0.5 - ?
305
Haemophilus influenzae
0.00625
0.0125
0.00313 - 0.0125
17
Haemophilus influenzae
≤0.03
≤0.03
≤0.03 - 0.06
1111
Haemophilus influenzae
(ampicillin-susceptible)
0.004
0.008
≤0.004 - 0.015
130
Haemophilus influenzae
(ampicillin-susceptible)
0.004
0.008
≤0.004 - 0.25
268
Haemophilus influenzae
(ampicillin-susceptible)
0.004
0.08
≤0.004 - 0.015
443
Haemophilus influenzae
(ESBL + ampicillin-resistant)
0.004
0.008
≤0.004 - 0.5
268
Haemophilus influenzae
(ESBL)
0.004
0.008
≤0.004 - 0.03
130
Haemophilus influenzae
(ESBL)
0.004
0.008
≤0.004 - 0.03
443
Haemophilus influenzae
(ESBL)
0.015
0.03
0.004 - 0.06
225
Haemophilus influenzae
(non-ESBL + ampicillin-resistant)
0.004
0.008
≤0.004 - 0.015
268
Haemophilus influenzae
(non-ESBL + ampicillin-resistant)
0.008
0.008
≤0.004 - 0.015
130
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