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Garenoxacin (T-3811, BMS-284756)
Garenoxacin (T-3811, BMS-284756)
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Haemophilus influenzae
(non-ESBL + ampicillin-resistant)
0.008
0.008
≤0.004 - 0.015
443
Haemophilus influenzae
(non-ESBL)
0.008
0.03
0.004 - 0.06
225
Klebsiella pneumonia
0.1
3.13
0.05 - 25
17
Klebsiella pneumonia
0.12
0.5
0.06 - 64
268
Klebsiella pneumonia
0.12
2
0.06 - 4
443
Klebsiella pneumonia
0.12
2
0.06 - 4
130
Klebsiella pneumonia
0.25
1
0.06 - 64
225
Klebsiella pneumonia
-
0.25
? - ?
1044
Klebsiella pneumonia
-
0.25
? - ?
1044
Klebsiella pneumonia
(ESBL)
1
64
0.06 - 64
225
Klebsiella
spp.
0.12
1
≤0.03 - >4
1250
Lactobacillus casei
0.125
0.25
0.06 - 1
1469
Lactobacillus
spp.
-
-
0.25 - ?
1476
Legionella pneumophila
0.002
0.008
≤0.001 - 0.015
225
Legionella pneumophila
0.004
0.008
0.004 - 0.06
268
Legionella pneumophila
0.008
0.008
≤0.004 - 0.008
443
Legionella pneumophila
0.008
0.008
≤0.004 - 0.008
130
Legionella
spp.
0.0156
0.0313
0.002 - 0.0313
17
Listeria monocytogenes
0.25
0.5
0.125 - 1
225
Moraxella catarrhalis
0.025
0.1
≤0.00625 - 0.39
17
Moraxella catarrhalis
0.03
0.03
≤0.004 - 0.06
130
Moraxella catarrhalis
0.03
0.03
≤0.004 - 0.06
443
Moraxella catarrhalis
≤0.03
≤0.03
≤0.03 - 0.12
1111
Moraxella catarrhalis
0.05
0.03
≤0.004 - 1
268
Moraxella catarrhalis
(ESBL)
0.06
0.06
0.03 - 0.125
225
Moraxella catarrhalis
(non-ESBL)
0.03
0.03
0.015 - 0.03
225
Morganella morganii
0.39
0.78
≤0.00625 - 6.25
17
Morganella morganii
2
32
0.25 - 64
225
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