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Quinupristin/Dalfopristin (Synercid)
Quinupristin/Dalfopristin (Synercid)
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Streptococcus oralis
-
-
2 - 4
178
Streptococcus parasanguis
0.5
1
<0.06 - 2
6
Streptococcus pneumonia
0.25
0.5
<0.06 - 2
6
Streptococcus pneumonia
0.5
2
0.25 - 2
448
Streptococcus pneumonia
0.75
0.125
≤0.03 - 8
162
Streptococcus pneumonia
-
0.75
? - ?
1112
Streptococcus pneumonia
(ATCC 49619)
-
-
0.5 - ?
401
Streptococcus pneumonia
(clinical isolate + pencillin-intermediate)
0.5
1
0.12 - 8
477
Streptococcus pneumonia
(clinical isolate + pencillin-resistant)
0.5
0.5
0.12 - 2
477
Streptococcus pneumonia
(clinical isolate + pencillin-susceptible)
0.5
0.5
≤0.06 - 2
477
Streptococcus pneumonia
(constitutively erm(B))
2
4
0.5 - 4
502
Streptococcus pneumonia
(erythromycin-resistant)
0.5
1
0.2 - 1
35
Streptococcus pneumonia
(erythromycin-susceptible)
1
2
0.5 - 2
502
Streptococcus pneumonia
(fluoroquinolone-resistant)
0.5
1
0.5 - 2
446
Streptococcus pneumonia
(macrolide-resistant)
-
-
0.285 - 1
49
Streptococcus pneumonia
(mef(A))
1
1
0.5 - 1
502
Streptococcus pneumonia
(multidrug-resistant)
0.25
0.5
<0.12 - 0.5
1060
Streptococcus pneumonia
(penicillin-intermediate)
0.5
0.5
0.25 - 1
462
Streptococcus pneumonia
(penicillin-intermediate)
0.5
0.5
0.25 - 1
265
Streptococcus pneumonia
(penicillin-intermediate)
0.5
0.5
? - ?
39
Streptococcus pneumonia
(penicillin-intermediate)
0.5
2
0.5 - 2
178
Streptococcus pneumonia
(penicillin-intermediate-resistant)
1
1
≤0.06 - 1
497
Streptococcus pneumonia
(penicillin-resistant)
<0.12
<0.03
<0.03 - ?
1060
Streptococcus pneumonia
(penicillin-resistant)
0.25
0.5
0.12 - 1
483
Streptococcus pneumonia
(penicillin-resistant)
0.5
0.5
0.25 - 1
462
Streptococcus pneumonia
(penicillin-resistant)
0.5
0.5
0.25 - 1
496
Streptococcus pneumonia
(penicillin-resistant)
0.5
0.5
? - ?
39
Streptococcus pneumonia
(penicillin-resistant)
0.5
0.5
? - ?
39
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