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Quinupristin/Dalfopristin (Synercid)
Quinupristin/Dalfopristin (Synercid)
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Streptococcus pneumonia
(penicillin-resistant)
0.5
1
0.5 - 1
178
Streptococcus pneumonia
(penicillin-resistant)
-
0.75
? - ?
1112
Streptococcus pneumonia
(penicillin-susceptible)
0.12
0.25
<0.12 - 0.25
1060
Streptococcus pneumonia
(penicillin-susceptible)
0.25
0.5
0.25 - 0.5
496
Streptococcus pneumonia
(penicillin-susceptible)
0.5
0.5
0.12 - 0.5
265
Streptococcus pneumonia
(penicillin-susceptible)
0.5
0.5
0.25 - 1
462
Streptococcus pneumonia
(penicillin-susceptible)
0.5
0.5
? - ?
39
Streptococcus pneumonia
(penicillin-susceptible)
0.5
1
0.5 - 1
178
Streptococcus pneumonia
(penicillin-susceptible)
-
0.5
? - ?
1112
Streptococcus pneumonia
(preclinical isolate + pencillin-intermediate)
0.5
1
≤0.06 - 2
477
Streptococcus pneumonia
(preclinical isolate + pencillin-resistant)
0.25
1
≤0.06 - 2
477
Streptococcus pneumonia
(preclinical isolate + pencillin-susceptible)
0.25
0.5
≤0.06 - 4
477
Streptococcus pyogenes
0.06
0.25
≤0.06 - 2
477
Streptococcus pyogenes
0.25
0.5
≤0.06 - 4
477
Streptococcus pyogenes
0.25
0.5
0.12 - 1
98
Streptococcus pyogenes
≤-
≤0.12
? - ?
1112
Streptococcus pyogenes
(constitutively erm(B))
0.5
1
0.5 - 1
502
Streptococcus pyogenes
(constitutively erm(TR))
-
-
0.25 - ?
502
Streptococcus pyogenes
(erythromycin-resistant)
0.2
0.2
0.1 - 0.5
35
Streptococcus pyogenes
(erythromycin-resistant)
≤-
≤0.12
? - ?
1112
Streptococcus pyogenes
(erythromycin-susceptible)
0.2
0.2
0.1 - 0.2
35
Streptococcus pyogenes
(erythromycin-susceptible)
0.5
1
0.25 - 1
502
Streptococcus pyogenes
(erythromycin-susceptible)
≤-
≤0.12
? - ?
1112
Streptococcus pyogenes
(inducible erm(B) + mef(A))
-
-
0.5 - ?
502
Streptococcus pyogenes
(inducible + erm(B))
-
-
0.5 - ?
502
Streptococcus pyogenes
(inducible erm(TR) + mef(A))
-
-
0.25 - ?
502
Streptococcus pyogenes
(inducible erm(TR))
0.5
0.5
0.25 - 1
502
Streptococcus pyogenes
(mef(A))
0.5
0.5
0.25 - 1
502
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