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Quinupristin/Dalfopristin (Synercid)
Quinupristin/Dalfopristin (Synercid)
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Staphylococcus aureus
(vancomycin-susceptible + Michigan strain)
-
-
0.5 - ?
273
Staphylococcus aureus
(vancomycin-susceptible + Pennsylvania strain)
-
-
0.25 - ?
273
Staphylococcus auricularis
0.25
0.5
≤0.25 - >8
472
Staphylococcus capitis
0.25
0.5
≤0.25 - >8
472
Staphylococcus capitis
(coagulase-negative)
0.125
0.25
≤0.06 - 1
497
Staphylococcus chromogenes
(coagulase-negative)
0.125
0.25
≤0.06 - 1
497
Staphylococcus cohnii
0.25
0.5
≤0.25 - >8
472
Staphylococcus epidermidis
0.25
0.5
≤0.25 - >8
472
Staphylococcus epidermidis
(clinical isolate + methicillin-resistant)
0.25
0.25
≤0.06 - 0.25
477
Staphylococcus epidermidis
(clinical isolate + methicillin-susceptible)
0.25
0.25
≤0.06 - 1
477
Staphylococcus epidermidis
(coagulase-negative)
0.125
0.25
≤0.06 - 1
497
Staphylococcus epidermidis
(methicillin-resistant)
0.06
0.25
0.06 - 8
7
Staphylococcus epidermidis
(methicillin-resistant)
<0.12
<0.12
<0.12 - ?
1060
Staphylococcus epidermidis
(methicillin-susceptible)
<0.12
<0.12
<0.12 - ?
1060
Staphylococcus epidermidis
(methicillin-susceptible)
0.12
0.25
≤0.12 - 0.5
186
Staphylococcus epidermidis
(methicillin-susceptible)
0.13
0.5
0.03 - 2
7
Staphylococcus epidermidis
(oxacillin-resistant)
0.25
0.25
≤0.12 - 0.5
496
Staphylococcus epidermidis
(preclinical isolate + methicillin-resistant)
0.25
0.5
≤0.06 - 16
477
Staphylococcus epidermidis
(preclinical isolate + methicillin-susceptible)
0.25
0.5
≤0.06 - 4
477
Staphylococcus haemolyticus
0.25
0.5
≤0.25 - >8
472
Staphylococcus haemolyticus
(coagulase-negative)
0.125
0.25
≤0.06 - 1
497
Staphylococcus haemolyticus
(oxacillin-resistant)
0.25
0.25
≤0.12 - 0.5
496
Staphylococcus haemolyticus
(oxacillin-susceptible)
0.25
-
≤0.12 - 0.5
496
Staphylococcus hominis
0.25
0.5
≤0.25 - >8
472
Staphylococcus hominis
(coagulase-negative)
0.125
0.25
≤0.06 - 1
497
Staphylococcus intermedius
0.5
1
<0.06 - 2
6
Staphylococcus lugdunensis
0.25
0.5
≤0.25 - >8
472
Staphylococcus saprophyticus
0.25
0.5
≤0.25 - >8
472
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