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Quinupristin/Dalfopristin (Synercid)
Quinupristin/Dalfopristin (Synercid)
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Staphylococcus aureus
(methicillin-susceptible)
-
0.375
? - ?
1112
Staphylococcus aureus
(meticillin-resistant)
0.5
1
0.5 - 1
1130
Staphylococcus aureus
(meticillin-susceptible)
0.5
0.5
0.25 - 1
1130
Staphylococcus aureus
(MU3 + vancomycin-intermediate)
-
-
1 - ?
1034
Staphylococcus aureus
(MU50 + vancomycin-intermediate)
-
-
1 - ?
1034
Staphylococcus aureus
(N95)
-
-
0.5 - ?
1028
Staphylococcus aureus
(oxacillin-resistant)
0.5
0.5
0.12 - 2
265
Staphylococcus aureus
(oxacillin-resistant)
0.5
0.5
0.25 - 1
446
Staphylococcus aureus
(oxacillin-resistant)
0.5
0.5
0.25 - 1
496
Staphylococcus aureus
(oxacillin-resistant)
0.5
1
? - ?
39
Staphylococcus aureus
(oxacillin-susceptible)
0.25
0.5
0.12 - 0.5
265
Staphylococcus aureus
(oxacillin-susceptible)
0.25
0.5
≤0.12 - 0.5
496
Staphylococcus aureus
(oxacillin-susceptible)
0.25
0.5
? - ?
39
Staphylococcus aureus
(pork isolate + Korea)
-
-
1 - ?
901
Staphylococcus aureus
(preclinical isolate + methicillin-resistant)
0.5
1
≤0.06 - 16
477
Staphylococcus aureus
(preclinical isolate + methicillin-susceptible)
0.5
1
≤0.06 - 4
477
Staphylococcus aureus
(RN1024)
-
-
0.5 - ?
601
Staphylococcus aureus
(RN1024-tms)
-
-
0.25 - ?
601
Staphylococcus aureus
(RN4220 + pCU1)
-
-
0.125 - ?
601
Staphylococcus aureus
(RN4220 + pCU1vgaAv)
-
-
1 - ?
601
Staphylococcus aureus
(RN4220 + pVGA)
-
-
0.5 - ?
601
Staphylococcus aureus
(RN4220)
-
-
0.125 - ?
601
Staphylococcus aureus
(RP13 + streptogramin A-resistant)
-
-
1 - ?
194
Staphylococcus aureus
(RP13)
-
-
1 - ?
1028
Staphylococcus aureus
(vancomycin-intermediate)
1
1
0.5 - 2
1130
Staphylococcus aureus
(vancomycin-intermediate-susceptible)
-
-
0.25 - 0.25
7
Staphylococcus aureus
(vancomycin-resistant)
0.5
-
0.5 - 1
1130
Staphylococcus aureus
(vancomycin-resistant)
-
-
0.25 - ?
57
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