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Quinupristin/Dalfopristin (Synercid)
Quinupristin/Dalfopristin (Synercid)
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Staphylococcus saprophyticus
(coagulase-negative)
0.125
0.25
≤0.06 - 1
497
Staphylococcus sciuri
0.25
0.5
≤0.25 - >8
472
Staphylococcus simulans
0.25
0.5
≤0.25 - >8
472
Staphylococcus simulans
0.25
2
0.25 - 2
446
Staphylococcus
spp.
0.25
0.5
≤0.25 - >8
472
Staphylococcus
spp. (coagulase-negative)
0.25
0.5
≤0.12 - 1
496
Staphylococcus
spp. (glycopeptide-intermediate)
0.5
0.5
<0.25 - 1
273
Staphylococcus warneri
0.25
0.5
≤0.25 - >8
472
Staphylococcus warneri
0.5
1
0.25 - 1
446
Staphylococcus warneri
(coagulase-negative)
0.125
0.25
≤0.06 - 1
497
Staphylococcus xylosus
0.25
0.5
≤0.25 - >8
472
Streptococci (serogroup A)
0.5
1
0.12 - 2
448
Streptococci (serogroup B)
2
4
1 - 4
448
Streptococci (serogroup C)
0.25
0.25
0.06 - 0.25
246
Streptococci (serogroup D)
>2
>2
≤0.25 - >2
472
Streptococci (serogroup G)
0.25
0.25
0.125 - 0.25
246
Streptococci (Viridans group + erythromycin-resistant)
-
1
? - ?
1112
Streptococci (Viridans group + penicillin-intermediate)
0.5
1
? - ?
39
Streptococci (Viridans group + penicillin-resistant)
-
1
? - ?
1112
Streptococci (Viridans group + penicillin-susceptible)
0.5
1
? - ?
39
Streptococci (Viridans group + penicillin-susceptible)
-
1
? - ?
1112
Streptococci (Viridans group)
0.25
0.5
<0.12 - 0.5
1060
Streptococci (Viridans group)
0.5
1
≤0.06 - 4
265
Streptococci (Viridans group)
-
0.75
? - ?
1112
Streptococci (α-hemolytic)
2
4
1 - 4
448
Streptococci (β-haemolytic + serogroup A)
≤0.12
≤0.12
≤0.12 - 0.5
462
Streptococci (β-haemolytic + serogroup B)
0.25
0.25
≤0.12 - 0.5
462
Streptococci (β-haemolytic + serogroup C)
0.25
0.5
≤0.12 - 0.5
462
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