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Daptomycin (Cubicin)
Daptomycin (Cubicin)
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Staphylococcus aureus
(1998)
1
2
≤0.06 - 2
907
Staphylococcus aureus
(1999)
1
2
0.5 - 2
907
Staphylococcus aureus
(2005)
1
2
≤0.06 - 2
907
Staphylococcus aureus
(3055)
-
-
0.5 - ?
1261
Staphylococcus aureus
(32 + methicillin-resistant)
-
-
0.25 - ?
1034
Staphylococcus aureus
(33 + methicillin-resistant)
-
-
0.25 - ?
1034
Staphylococcus aureus
(42)
-
-
0.5 - 1
541
Staphylococcus aureus
(494 + methicillin-resistant)
-
-
0.25 - ?
82
Staphylococcus aureus
(494 + methicillin-resistant)
-
-
0.25 - ?
92
Staphylococcus aureus
(5023 + methicillin-resistant)
-
-
0.25 - ?
1034
Staphylococcus aureus
(559)
-
-
0.5 - ?
82
Staphylococcus aureus
(8 + methicillin-susceptible)
-
-
0.5 - ?
207
Staphylococcus aureus
(8 + methicillin-susceptible)
-
-
0.5 - ?
72
Staphylococcus aureus
(9 + methicillin-susceptible)
-
-
0.5 - ?
207
Staphylococcus aureus
(ATCC 25923)
-
-
0.13 - 0.25
7
Staphylococcus aureus
(ATCC 25923)
-
-
0.5 - ?
127
Staphylococcus aureus
(ATCC 29213)
-
-
0.5 - ?
127
Staphylococcus aureus
(ATCC 33591)
-
-
0.5 - ?
127
Staphylococcus aureus
(ATCC 6538p)
-
-
0.5 - ?
127
Staphylococcus aureus
(community-acquired + methicillin-resistant)
0.25
0.5
0.25 - 1
110
Staphylococcus aureus
(community-associated + methicillin-resistant)
0.12
0.25
0.06 - 1
1376
Staphylococcus aureus
(glycopeptide-intermediate)
1
4
0.5 - 16
16
Staphylococcus aureus
(glycopeptide-intermediate)
4
16
2 - 16
16
Staphylococcus aureus
(glycopeptide-intermediate-susceptible)
-
-
0.25 - 2
1261
Staphylococcus aureus
(health care-associated + methicillin-resistant)
0.25
0.25
0.12 - 1
1376
Staphylococcus aureus
(Hershey + vancomycin-resistant)
-
-
0.5 - ?
1034
Staphylococcus aureus
(linezolid-resistant)
1
2
≤0.12 - 4
483
Staphylococcus aureus
(methicillin-resistant)
0.13
0.13
0.06 - 0.5
7
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