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Daptomycin (Cubicin)
Daptomycin (Cubicin)
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Staphylococcus aureus
(methicillin-resistant)
0.25
0.5
0.25 - 0.5
16
Staphylococcus aureus
(methicillin-resistant)
0.5
0.5
0.12 - 1
73
Staphylococcus aureus
(methicillin-resistant)
0.5
0.5
0.25 - 4
72
Staphylococcus aureus
(methicillin-resistant)
2
2
1 - 4
16
Staphylococcus aureus
(methicillin-resistant)
-
0.5
? - ?
1112
Staphylococcus aureus
(methicillin-resistant)
-
1
? - ?
1358
Staphylococcus aureus
(methicillin-resistant)
-
-
0.125 - ?
57
Staphylococcus aureus
(methicillin-resistant)
-
-
1 - ?
57
Staphylococcus aureus
(methicillin-susceptible)
0.13
0.13
0.06 - 0.5
7
Staphylococcus aureus
(methicillin-susceptible)
0.25
0.5
0.12 - 0.5
16
Staphylococcus aureus
(methicillin-susceptible)
0.25
0.5
0.12 - 0.5
73
Staphylococcus aureus
(methicillin-susceptible)
0.25
0.5
0.125 - 0.5
72
Staphylococcus aureus
(methicillin-susceptible)
0.5
0.5
0.125 - 1
207
Staphylococcus aureus
(methicillin-susceptible)
1
2
1 - 2
16
Staphylococcus aureus
(methicillin-susceptible)
-
0.5
? - ?
1112
Staphylococcus aureus
(methicillin-susceptible)
-
0.5
? - ?
1358
Staphylococcus aureus
(meticillin-resistant)
-
-
0.06 - 2
1261
Staphylococcus aureus
(meticillin-susceptible)
-
-
0.03 - 2
1261
Staphylococcus aureus
(MU3 + vancomycin-intermediate)
-
-
0.25 - ?
1034
Staphylococcus aureus
(MU50 + vancomycin-intermediate)
-
-
0.25 - ?
1034
Staphylococcus aureus
(pork isolate + Korea)
-
-
2 - ?
901
Staphylococcus aureus
(ST201 + meticillin-resistant)
-
-
0.5 - ?
1261
Staphylococcus aureus
(ST210 + meticillin-resistant)
-
-
1 - ?
1261
Staphylococcus aureus
(ST329 + meticillin-resistant)
-
-
0.5 - ?
1261
Staphylococcus aureus
(ST56 + meticillin-resistant)
-
-
2 - ?
1261
Staphylococcus aureus
(ST57 + meticillin-resistant)
-
-
1 - ?
1261
Staphylococcus aureus
(ST59 + meticillin-resistant)
-
-
1 - ?
1261
Staphylococcus aureus
(ST60 + meticillin-resistant)
-
-
0.5 - ?
1261
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