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Daptomycin (Cubicin)
Daptomycin (Cubicin)
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Staphylococcus aureus
(vancomycin-intermediate)
-
4
? - ?
1358
Staphylococcus aureus
(vancomycin-intermediate-susceptible)
-
-
0.5 - 1
7
Staphylococcus aureus
(vancomycin-resistant)
-
1
? - ?
1358
Staphylococcus aureus
(vancomycin-resistant)
-
-
0.25 - ?
57
Staphylococcus aureus
Vero (methicillin-resistant)
0.5
0.5
0.125 - 2
207
Staphylococcus auricularis
0.25
0.5
0.06 - 2
472
Staphylococcus capitis
0.25
0.5
0.06 - 2
472
Staphylococcus cohnii
0.25
0.5
0.06 - 2
472
Staphylococcus epidermidis
0.25
0.5
0.06 - 2
472
Staphylococcus epidermidis
1
2
0.06 - 4
37
Staphylococcus epidermidis
1
2
0.5 - 8
37
Staphylococcus epidermidis
(glycopeptide-intermediate-susceptible)
-
-
0.5 - 1
1261
Staphylococcus epidermidis
(linezolid-resistant)
1
2
≤0.12 - 4
483
Staphylococcus epidermidis
(methicillin-resistant)
0.13
0.25
0.13 - 2
7
Staphylococcus epidermidis
(methicillin-susceptible)
0.13
0.5
0.06 - 1
7
Staphylococcus epidermidis
(meticillin-resistant)
-
-
0.06 - 1
1261
Staphylococcus epidermidis
(meticillin-susceptible)
-
-
0.06 - 0.5
1261
Staphylococcus epidermidis
(ST277 + meticillin-resistant)
-
-
1 - ?
1261
Staphylococcus epidermidis
(ST278 + meticillin-resistant)
-
-
1 - ?
1261
Staphylococcus haemolyticus
0.25
0.5
0.06 - 2
472
Staphylococcus haemolyticus
0.25
0.5
0.06 - 2
472
Staphylococcus haemolyticus
-
-
0.03 - 1
1261
Staphylococcus haemolyticus
-
-
1 - ?
1261
Staphylococcus haemolyticus
(methicillin-resistant)
-
2
? - ?
1112
Staphylococcus hominis
0.25
0.5
0.06 - 2
472
Staphylococcus lugdunensis
0.25
0.5
0.06 - 2
472
Staphylococcus pneumonia
-
-
0.0075 - 0.06
1261
Staphylococcus pneumonia
(Park I)
-
-
0.12 - ?
1261
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