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Telithromycin (HMR 3647, RU-66647, Ketek)
Telithromycin (HMR 3647, RU-66647, Ketek)
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Streptococcus pneumonia
(1999-2000)
-
0.12
≤0.002 - 8
275
Streptococcus pneumonia
(2000-2001)
-
0.12
≤0.002 - 8
275
Streptococcus pneumonia
(2001-2002)
-
0.12
≤0.002 - 8
275
Streptococcus pneumonia
(2002-2003)
-
0.12
≤0.002 - 8
275
Streptococcus pneumonia
(50S ribosomal mutations)
0.015
0.12
≤0.008 - 0.5
1111
Streptococcus pneumonia
(6396 + MLSB-resistant)
-
-
0.125 - ?
319
Streptococcus pneumonia
(ATCC 49619)
-
-
0.008 - ?
401
Streptococcus pneumonia
(ATCC 5649 + efflux-resistant)
-
-
0.5 - ?
319
Streptococcus pneumonia
(ATCC 5649)
-
-
0.5 - ?
319
Streptococcus pneumonia
(ATCC 5737)
-
-
8 - ?
319
Streptococcus pneumonia
(ATCC 6303 + erythromycin-susceptible)
-
-
0.004 - ?
319
Streptococcus pneumonia
(ATCC 6303 + erythromycin-susceptible)
-
-
0.004 - ?
319
Streptococcus pneumonia
(ATCC 6303)
-
-
0.004 - ?
319
Streptococcus pneumonia
(clindamycin-resistant)
≤0.12
≤0.12
? - ?
18
Streptococcus pneumonia
(clindamycin-susceptible)
≤0.12
≤0.12
? - ?
18
Streptococcus pneumonia
(constitutively erm(B))
0.063
0.25
≤0.008 - 0.25
502
Streptococcus pneumonia
(erm(B) + mef(A))
-
-
≤0.002 - 0.004
331
Streptococcus pneumonia
(erm(B) + mef(A))
-
-
≤0.002 - 0.06
331
Streptococcus pneumonia
(erm(B) + mef)
0.5
0.5
0.002 - 1
1113
Streptococcus pneumonia
(erm(B) + mef)
0.5
0.5
0.002 - 1
954
Streptococcus pneumonia
(erm(B))
0.008
0.016
≤0.008 - 0.5
1111
Streptococcus pneumonia
(erm(B))
0.03
0.125
0.008 - 1
1113
Streptococcus pneumonia
(erm(B))
0.06
0.12
≤0.001 - >=64
950
Streptococcus pneumonia
(erm(B))
0.06
0.25
0.004 - 8
954
Streptococcus pneumonia
(erm(B))
0.06
0.25
0.004 - 8
1113
Streptococcus pneumonia
(erm(B))
-
0.06
≤0.02 - 1
331
Streptococcus pneumonia
(erm(B), L4)
-
-
256 - ?
1111
Streptococcus pneumonia
(erythromycin A-resistant)
0.12
0.25
≤0.12 - 32
499
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