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Telithromycin (HMR 3647, RU-66647, Ketek)
Telithromycin (HMR 3647, RU-66647, Ketek)
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Staphylococcus aureus
(methicillin-susceptible)
0.06
0.12
0.015 - >128
948
Staphylococcus aureus
(methicillin-susceptible)
0.12
0.12
0.06 - >8
73
Staphylococcus aureus
(meticillin-resistant)
>0.25
>16
0.06 - >16
1130
Staphylococcus aureus
(meticillin-susceptible)
0.12
0.25
0.06 - >16
1130
Staphylococcus aureus
(mrsA)
-
-
<0.2 - ?
947
Staphylococcus aureus
(msr(A))
0.12
0.12
0.015 - 1
954
Staphylococcus aureus
(msr(A))
0.12
0.12
0.015 - 1
1113
Staphylococcus aureus
(oxacillin-resistant)
>16
>16
0.06 - >16
496
Staphylococcus aureus
(oxacillin-resistant)
>16
>16
≤0.12 - >16
18
Staphylococcus aureus
(oxacillin-susceptible)
≤0.12
≤0.12
≤0.12 - >16
18
Staphylococcus aureus
(SJ0301 + constitutively erythromycin-resistant)
-
-
0.08 - ?
58
Staphylococcus aureus
(vancomycin-intermediate)
>16
>16
0.25 - >16
1130
Staphylococcus aureus
(vancomycin-resistant)
16
-
0.12 - >16
1130
Staphylococcus epidermidis
(oxacillin-resistant)
>16
>16
0.06 - >16
496
Staphylococcus epidermidis
(oxacillin-susceptible)
0.06
0.25
0.06 - >16
496
Staphylococcus haemolyticus
(oxacillin-susceptible)
0.06
-
0.06 - >16
496
Staphylococcus pneumonia
(erm(B))
-
-
0.003 - ?
947
Staphylococcus pneumonia
(ery(S))
-
-
0.003 - ?
947
Staphylococcus pneumonia
(mef(E))
-
-
0.39 - ?
947
Staphylococcus pyogenes
(erm(B))
-
-
8 - ?
947
Staphylococcus pyogenes
(ery(S))
-
-
<0.13 - ?
947
Staphylococcus pyogenes
(mef(A))
-
-
0.5 - ?
947
Staphylococcus
spp. (coagulase-negative + clindamycin-resistant)
>16
>16
? - ?
18
Staphylococcus
spp. (coagulase-negative)
>0.06
>16
0.03 - >16
496
Staphylococcus
spp. (serogroup C)
≤0.12
≤0.12
≤0.12 - 4
18
Staphylococcus
spp. (serogroup F)
≤0.12
≤0.12
≤0.12 - 4
18
Staphylococcus
spp. (serogroup G)
≤0.12
≤0.12
≤0.12 - 4
18
Stomatococcus
spp.
≤0.12
≤0.12
≤0.12 - >16
18
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