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Telithromycin (HMR 3647, RU-66647, Ketek)
Telithromycin (HMR 3647, RU-66647, Ketek)
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Staphylococcus aureus
(ATCC 29213)
-
-
0.06 - ?
401
Staphylococcus aureus
(ATCC 5177)
-
-
0.1 - ?
319
Staphylococcus aureus
(ATCC 5278)
-
-
>100 - ?
319
Staphylococcus aureus
(ATCC 6538P)
-
-
0.1 - ?
319
Staphylococcus aureus
(ATCC 6571)
-
-
0.03 - ?
401
Staphylococcus aureus
(community-associated + meticillin-resistant)
0.25
0.25
0.12 - 0.5
1130
Staphylococcus aureus
(constitutively erm(A) + constitutively erm(C))
>128
>128
0.3 - >128
1113
Staphylococcus aureus
(constitutively erm(A) + constitutively erm(C))
>128
>128
0.3 - >128
954
Staphylococcus aureus
(erm(A)-inducible)
0.125
0.25
0.06 - 12
1113
Staphylococcus aureus
(erm(C))
-
-
<0.2 - ?
947
Staphylococcus aureus
(Ery S)
-
-
<0.2 - ?
947
Staphylococcus aureus
(erythromycin A-resistant)
>=2
≥64
0.03 - >=64
950
Staphylococcus aureus
(erythromycin A-susceptible)
0.06
0.06
0.008 - 0.5
950
Staphylococcus aureus
(erythromycin-resistant + constitutively erm resistant mechanism)
>128
>128
>128 - ?
16
Staphylococcus aureus
(erythromycin-resistant + inducible erm resistant mechanism)
0.12
25
0.06 - 0.5
162
Staphylococcus aureus
(erythromycin-resistant + methicillin-resistant)
>64
>64
32 - >64
448
Staphylococcus aureus
(erythromycin-resistant + methicillin-susceptible)
-
-
0.03 - >32
448
Staphylococcus aureus
(erythromycin-resistant + msr resistant mechanism)
0.06
0.12
≤0.015 - 0.25
162
Staphylococcus aureus
(erythromycin-resistant)
>16
>16
? - ?
496
Staphylococcus aureus
(erythromycin-susceptible + methicillin-susceptible)
0.03
0.06
0.03 - 0.06
448
Staphylococcus aureus
(erythromycin-susceptible)
0.06
0.06
? - ?
496
Staphylococcus aureus
(erythromycin-susceptible)
0.06
0.12
0.015 - 0.25
1113
Staphylococcus aureus
(erythromycin-susceptible)
0.06
0.12
≤0.015 - 0.25
162
Staphylococcus aureus
(erythromycin-susceptible)
0.06
0.12
0.015 - 0.25
954
Staphylococcus aureus
(heterogeneous + vancomycin-intermediate)
>16
>16
0.25 - >16
1130
Staphylococcus aureus
(methicillin-resistant)
>0.12
>8
≤0.03 - >8
73
Staphylococcus aureus
(methicillin-resistant)
>16
>16
0.03 - >128
948
Staphylococcus aureus
(methicillin-susceptible)
0.03
0.06
0.03 - >32
448
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